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Also called: Also called: Non-Hodgkin's lymphoma

Lymphoma is a cancer of a part of the immune system called the lymphatic system. There are many types of lymphoma. One type is called Hodgkin's disease. The rest are called non-Hodgkin's lymphoma.

Non-Hodgkin's lymphomas begin when a type of white blood cell, called a T cell or B cell, becomes abnormal. The cell divides again and again, making more and more abnormal cells. These abnormal cells can spread to almost any other part of the body. Most of the time, doctors can't determine why a person gets non-Hodgkin's lymphoma.

Non-Hodgkin's lymphoma can cause many symptoms, such as

Swollen, painless lymph nodes in the neck, armpits or groin
Unexplained weight loss
Fever
Soaking night sweats
Coughing, trouble breathing or chest pain
Weakness and tiredness that don't go away
Pain, swelling or a feeling of fullness in the abdomen

Your doctor will per! form an exam and lab tests to determine if you have lymphoma.

National Cancer Institute

Start Here

What Is Non-Hodgkin Lymphoma?(American Cancer Society) - http://www.cancer.org/docroot/cri/content/cri_2_4_1x_what_is_non_hodgkins_lymphoma_32.asp

Also available in Spanish http://www.cancer.org/docroot/esp/content/esp_5_1x_que_es_32.asp?
What You Need to Know about Non-Hodgkin Lymphoma(National Cancer Institute) - http://www.cancer.gov/cancertopics/wyntk/non-hodgkins-lymphoma

Overviews

Lymphomas: A Guide for Patients and Caregivers(Leukemia & Lymphoma Society) - Large PDF file - http://www.leukemia-lymphoma.org/attachments/National/br_1178218354.pdf

Also available in Spanish http://www.leukemia-lymphoma.org/attachments/National/br_1139861955.pdf

Latest News

Incidence of Mantle Cell Lymphoma on Rise(07/18/2008, HealthDay) - http://www.nlm.nih.gov/medlineplus/news/fullstory_67140.html
Antidepressants Linked to Non-Hodgkin Lymphoma(07/18/2008, Reuters Health) - http://www.nlm.nih.gov/medlineplus/news/fullstory_67103.html

Diagnosis/Symptoms

How Is Non-Hodgkin Lymphoma Diagnosed?(American Cancer Society) - http://www.cancer.org/docroot/cri/content/cri_2_4_3x_how_is_non-hodgkins_lymphoma_diagnosed_32.asp

Also available in Spanish http://www.cancer.org/docroot/esp/content/esp_5_1x_deteccion_y_sintomas_32.asp?
How Is Non-Hodgkin Lymphoma Staged?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_3X_How_is_non-Hodgkins_lymphoma_staged_32.asp?rnav=cri
How Is Waldenstrom Macroglobulinemia Diagnosed?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_3x_How_Is_Waldenstroms_Macroglobulinemia_Diagnosed.asp?rnav=cri
Understanding Blood Counts(Leukemia & Lymphoma Society) - http://www.leukemia-lymphoma.org/all_mat_toc.adp?item_id=9452

Also available in Spanish http://www.leukemia-lymphoma.org/all_mat_toc.adp?item_id=186980

Treatment

Adult Non-Hodgkin's Lymphoma (PDQ): Treatment(National Cancer Institute) - http://www.cancer.gov/cancertopics/pdq/treatment/adult-non-hodgkins/patient/

Also available in Spanish http://www.cancer.gov/espanol/pdq/tratamiento/no-hodgkin-adultos/patient/
AIDS-Related Lymphoma (PDQ): Treatment(National Cancer Institute) - http://www.cancer.gov/cancertopics/pdq/treatment/AIDS-related-lymphoma/patient/

Also available in Spanish http://www.cancer.gov/espanol/pdq/tratamiento/linfoma-y-SIDA/patient/
MedlinePlus: Bone Marrow Transplantation(National Library of Medicine) - http://www.nlm.nih.gov/medlineplus/bonemarrowtransplantation.html

Also available in Spanish http://www.nlm.nih.gov/medlineplus/spanish/bonemarrowtransplantation.html
Mycosis Fungoides and the Sezary Syndrome (PDQ): Treatment(National Cancer Institute) - http://www.cancer.gov/cancertopics/pdq/treatment/mycosisfungoides/patient/

Also available in Spanish http://www.cancer.gov/espanol/pdq/tratamiento/micosisfungoide/patient
New Approaches to Treatment(Leukemia & Lymphoma Society) - http://www.leukemia-lymphoma.org/all_page?item_id=4702
Primary CNS Lymphoma (PDQ): Treatment(National Cancer Institute) - http://www.cancer.gov/cancertopics/pdq/treatment/primary-CNS-lymphoma/patient/

Also available in Spanish http://www.cancer.gov/espanol/pdq/tratamiento/linfoma-sistema-nervioso-central/patient/
Radiation Therapy for Non-Hodgkins Lymphoma(American Society for Therapeutic Radiology and Oncology) - http://www.rtanswers.org/treatment/disease/non_hodgkins.htm
Treatment of Extranodal Non-Hodgkin's Lymphoma(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_4X_Treatment_of_Extranodal_Non-Hodgkins_Lymphoma_32.asp
Treatment of Intermediate Grade Non-Hodgkin's Lymphoma -- Stages I and II(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_4X_Treatment_of_Intermediate_Grade_Non-Hodgkins_Lymphoma_--_Stages_I_and_II_32.asp?sitearea=
Treatment of Intermediate Grade Non-Hodgkin's Lymphoma -- Stages III and IV and High Grade Lymphomas(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_4X_Treatment_of_Intermediate_Grade_Non-Hodgkins_Lymphoma_--_Stages_III_and_IV_and_High_Grade_Lymphomas_32.asp?sitearea=
Treatment of People with Waldenstrom Macroglobulinemia(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_4x_Treatment_of_People_with_Waldenstrom_Macroglobulinemia_76.asp?rnav=cri
Understanding Drug Therapy and Managing Side Effects(Leukemia & Lymphoma Society) - Large PDF file - http://www.leukemia-lymphoma.org/attachments/National/br_1171992654.pdf

Also available in Spanish http://www.leukemia-lymphoma.org/all_mat_toc.adp?item_id=203943

Prevention/Screening

Can Non-Hodgkin Lymphoma Be Prevented?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_Can_non-Hodgkins_lymphoma_be_prevented_32.asp
What Are the Risk Factors for Non-Hodgkin Lymphoma?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_What_are_the_risk_factors_for_non-Hodgkins_lymphoma_32.asp
What Are the Risk Factors for Waldenstrom Macroglobulinemia?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_2x_What_Are_The_Risk_Factors_For_Waldenstroms_Macroglobulinemia.asp?rnav=cri

Alternative Therapy

Integrative Medicine & Complementary and Alternative Therapies As Part of Blood Cancer Care(Leukemia & Lymphoma Society) - Links to PDF - http://www.leukemia-lymphoma.org/attachments/National/br_1150734030.pdf

Coping

Coping with Lymphoma(Lymphoma Research Foundation) - http://www.lymphomafacts.org/site/c.gtJSJbMUIuE/b.1267819/k.608A/Coping_with_Lymphoma.htm
Relationships and Recovery for Young Adult Lymphoma Survivors(Lymphoma Research Foundation) - http://www.lymphoma.org/site/pp.asp?c=chKOI6PEImE&b=2705045

Disease Management

Lymphoma, Non-Hodgkin Type: What Happens After Treatment?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_5X_What_happens_after_treatment_32.asp?sitearea=
What Happens After Treatment of Waldenstrom Macroglobulinemia?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_5x_What_Happens_After_Treatment_of_Waldenstroms_Macroglobulinemia.asp?rnav=cri

Specific Conditions

Common Types of Non-Hodgkin Lymphoma(Lymphoma Research Foundation) - http://www.lymphoma.org/site/pp.asp?c=chKOI6PEImE&b=1573973
Cutaneous T Cell Lymphoma(Leukemia & Lymphoma Society) - Links to PDF - http://www.leukemia-lymphoma.org/attachments/National/br_1163608564.pdf

Also available in Spanish http://www.leukemia-lymphoma.org/attachments/National/br_1199384874.pdf
Waldenstrom's Macroglobulinemia(National Cancer Institute) - http://www.cancer.gov/cancertopics/factsheet/Sites-Types/WM

Related Issues

Hodgkin's vs. Non-Hodgkin's Lymphoma: What's the Difference?(Mayo Foundation for Medical Education and Research) - http://www.mayoclinic.com/print/lymphoma/AN01209/METHOD=print
Pain Management(Leukemia & Lymphoma Society) - Links to PDF - http://www.leukemia-lymphoma.org/attachments/National/br_1208959618.pdf
What You Should Know Before Starting Treatment(Lymphoma Research Foundation) - http://www.lymphoma.org/site/pp.asp?c=chKOI6PEImE&b=1573963

Anatomy/Physiology

Atlas of the Body: The Lymphatic System(American Medical Association) - http://www.medem.com/medlb/article_detaillb.cfm?article_ID=ZZZG0S6CGJC&sub_cat=518

Financial Issues

Financial Support(Leukemia & Lymphoma Society) - http://www.leukemia-lymphoma.org/all_page?item_id=4599
Patient Aid Grant and Healthcare Provider Grant Program(Lymphoma Research Foundation) - http://www.lymphoma.org/site/pp.asp?c=chKOI6PEImE&b=2577325

Clinical Trials

ClinicalTrials.gov: Lymphoma(National Institutes of Health) - http://clinicaltrials.gov/search/open/condition=%22Lymphoma%22
ClinicalTrials.gov: Lymphoma, Non-Hodgkin(National Institutes of Health) - http://clinicaltrials.gov/search/open/condition=%22Lymphoma,+Non-Hodgkin%22

Research

Antibiotics Work Against Eye Lymphoma(American Cancer Society) - http://www.cancer.org/docroot/NWS/content/NWS_1_1x_Antibiotics_Work_Against_Eye_Lymphoma.asp
Initial Treatment with Rituximab Is a New Standard for Elderly Patients with B-Cell Lymphoma(National Cancer Institute) - http://www.cancer.gov/clinicaltrials/results/elderly-rituximab0706
Less-Intense Chemotherapy Benefits Some Children with B-Cell Non-Hodgkin Lymphoma(National Cancer Institute) - http://www.cancer.gov/clinicaltrials/results/pediatricNHL0407
Radiation Might be Avoided for Older Patients with Good Prognosis Non-Hodgkin's Lymphoma(National Cancer Institute) - http://www.cancer.gov/clinicaltrials/results/CHOPalone0207
Rituximab Helps Patients with Recurrent Lymphomas(National Cancer Institute) - http://www.cancer.gov/clinicaltrials/results/rituximab1106
Rituximab Improves Response Rate in Mantle Cell Lymphoma(National Cancer Institute) - http://www.cancer.gov/clinicaltrials/results/Rituximab0604
What's New in Non-Hodgkin Lymphoma Research and Treatment?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_6X_Whats_new_in_non-Hodgkins_lymphoma_research_and_treatment_32.asp

Journal Articles

References and abstracts from MEDLINE/PubMed (National Library of Medicine)

Article: AJR teaching file: incidental hepatic mass. - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=18492933&tool=MedlinePlus
Article: Lymphoma in common variable immunodeficiency: interplay between immune dysregulation, infection... - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=18536576&tool=MedlinePlus
Article: Primary central nervous system lymphoma can be histologically diagnosed after... - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=18481293&tool=MedlinePlus
Lymphoma -- see more articles - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&term=(lymphoma[majr]+NOT+(hodgkin+disease[mh]+OR+lymphoma,non-hodgkin[mh]))+AND+english[la]+AND+humans[mh]+AND+(jsubsetk[text]+OR+review[pt]+OR+guideline[pt]+OR+patient+education+handout[pt]+OR+clinical+trial[pt]+OR+jsubsetaim[text]+OR+jsubsetn[text])+NOT+(letter[pt]+OR+editorial[pt])&doptcmdl=summary&cmd_current=Limits&pmfilter_EDatLimit=last+1+Year&tool=MedlinePlus
Non-hodgkin lymphoma -- see more articles - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&term=lymphoma,non+hodgkin[majr]+AND+english[la]+AND+humans[mh]+AND+(review[pt]+OR+guideline[pt]+OR+clinical+trial[pt]+OR+patient+education+handout[pt]+OR+jsubsetk[text]+OR+jsubsetaim[text]+OR+jsubsetn[text])+NOT+(letter[pt]+OR+editorial[pt]+OR+case+reports[pt])&doptcmdl=summary&cmd_current=Limits&pmfilter_EDatLimit=last+1+Year&tool=MedlinePlus

Dictionaries/Glossaries

Learning about Lymphoma: Glossary of Terms(Lymphoma Research Foundation) - http://www.lymphoma.org/site/pp.asp?c=chKOI6PEImE&b=1573585
Mantle Cell Lymphoma: Glossary(Lymphoma Research Foundation) - http://www.mantlecelllymphoma.org/site/c.mwKUJbNUJrF/b.4017103/k.D4C9/Glossary.htm

Organizations

American Cancer Society - http://www.cancer.org/
Leukemia & Lymphoma Society - http://www.leukemia-lymphoma.org/hm_lls
Lymphoma Research Foundation - http://www.lymphoma.org/
National Cancer Institute - http://www.cancer.gov/

Newsletters/Print Publications

Blood & Marrow Transplant Newsletter(BMT InfoNet) - http://www.bmtinfonet.org/letter.html

Statistics

Facts 2007-2008(Leukemia & Lymphoma Society) - Large PDF file - http://www.leukemia-lymphoma.org/attachments/National/br_1182779969.pdf
Non-Hodgkin Lymphoma Facts & Statistics(Leukemia & Lymphoma Society) - http://www.leukemia-lymphoma.org/all_page?item_id=8965
What Are the Key Statistics about Non-Hodgkin Lymphoma in Children?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_1x_What_are_the_key_statistics_for_childhood_non_Hodgkins_lymphoma_9.asp

Children

Bone Marrow Transplantation (BMT) and Peripheral Blood Stem Cell Transplantation (PBSCT)(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_4x_Bone_Marrow_Transplantation_and_Peripheral_Blood_Stem_Cell_Transplantation_9.asp
Childhood Cancer: Lymphoma(Nemours Foundation) - http://kidshealth.org/parent/medical/cancer/cancer_lymphoma.html

Also available in Spanish http://kidshealth.org/parent/en_espanol/medicos/cancer_lymphoma_esp.html
Childhood Non-Hodgkin Lymphoma (PDQ): Treatment(National Cancer Institute) - http://www.cancer.gov/cancertopics/pdq/treatment/child-non-hodgkins/patient/

Also available in Spanish http://www.cancer.gov/espanol/pdq/tratamiento/no-hodgkin-infantil/patient/
Do We Know What Causes Non-Hodgkin Lymphoma in Children?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_2x_Do_we_know_what_causes_childhood_non_hodgkins_lymphoma_9.asp?rnav=cri
How Is Childhood Non-Hodgkin Lymphoma Treated?(American Cancer Society) - http://www.cancer.org/docroot/cri/content/cri_2_2_4x_how_is_childhood_non-hodgkins_lymphoma_treated_9.asp
How Is Non-Hodgkin Lymphoma in Children Diagnosed?(American Cancer Society) - http://www.cancer.org/docroot/cri/content/cri_2_4_3x_how_is_childhood_non_hodgkins_lymphoma_diagnosed_9.asp
How Is Non-Hodgkin Lymphoma in Children Staged?(American Cancer Society) - http://www.cancer.org/docroot/cri/content/cri_2_4_3x_how_is_childhood_non_hodgkins_lymphoma_staged_9.asp
Long-Term and Late Effects of Treatment for Childhood Leukemia or Lymphoma(Leukemia & Lymphoma Society) - Links to PDF - http://www.leukemia-lymphoma.org/attachments/National/br_1184160690.pdf
Some Kinds of Cancer Kids Get(Nemours Foundation) - http://kidshealth.org/kid/health_problems/cancer/cancer_kinds.html

Also available in Spanish http://kidshealth.org/kid/en_espanol/enfermadades/cancer_kinds_esp.html
What Are the Risk Factors for Non-Hodgkin Lymphoma in Children?(American Cancer Society) - http://www.cancer.org/docroot/cri/content/cri_2_4_2x_what_are_the_risk_factors_for_childhood_non_hodgkins_lymphoma_9.asp
What's New in Non-Hodgkin Lymphoma in Children Research and Treatment?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_6x_Whats_new_in_childhood_non_hodgkins_lymphoma_research_and_treatment_9.asp

Teenagers

Non-Hodgkin's Lymphoma(Nemours Foundation) - http://kidshealth.org/teen/diseases_conditions/cancer/non_hodgkins.html

You may also be interested in these MedlinePlus related pages:

Hodgkin's Disease - http://www.nlm.nih.gov/medlineplus/hodgkinsdisease.html
Cancers - http://www.nlm.nih.gov/medlineplus/cancers.html
Immune System - http://www.nlm.nih.gov/medlineplus/immunesystem.html

The primary NIH organization for research on Lymphoma is the National Cancer Institute - http://www.nci.nih.gov/

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